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右正中神经电刺激对脑损伤术后昏迷患者催醒的临床研究


YOUZHENGZHONGSHENJINGDIANCIJIDUINAOSUNSHANGSHUHOUHUNMIHUANZHECUIXINGDELINCHUANGYANJIU


GUANGZHOUYIKEDAXUEFUSHUSHENZHENSHAJINGYIYUANSHENJINGWAIKE ,ZUOZHEJIANJIE:WANGSHIQIANGNAN,XUESHI,FUZHURENYISHI,CONGSHILUNAOSUNSHANG、NAOXUEGUANJIBINGJIUZHIJISHENJINGWAIKELINCHUANGYANJIU.


MUDE TANTAOYOUZHENGZHONGSHENJINGDIANCIJIDUINAOSUNSHANGSHUHOUHUNMIHUANZHEDELINCHUANGLIAOXIAO


FANGFA XUANQULUNAOSUNSHANGSHUHOUHUNMICHAOGUO 7 d、GELASIGEHUNMIPINGFEN(GCS)3~8 FENDENAOSUNSHANGHUANZHE 52 LI,SUIJIFENCHENGDUIZHAOZUHEZHILIAOZU,MEIZU 26 LI。


LIANGZUJUNYUCHANGGUIZHILIAO,ZHILIAOZUZAICHANGGUIZHILIAODEJICHUSHANGJIAXINGYOUZHENGZHONGSHENJINGDIANCIJIZHILIAO, BIJIAOLIANGZUHUANZHEZHILIAO 2 GEYUEHOU GCS PINGFEN、JFK HUNMIHUIFULIANGBIAOPINGFEN(CRS-R)、NAODIANTU(EEG)、NAOGANTINGJUEYOUFADIANWEI(BAEP)DEBIANHUAQINGKUANG。


JIEGUO ZHILIAO 2 GEYUEHOU,ZHILIAOZU GCS HE CRS-R PINGFENFENBIEWEI(11.01±1.19) HE(8.62±1.34), JIAODUIZHAOZUYOUMINGXIANGAISHAN(P<0.05); ZHILIAOZUDE EEG YIJI BAEP GAISHANXIAOGUOXIANZHUYOUYUDUIZHAOZU(P<0.05)。


JIELUN YOUZHENGZHONGSHENJINGDIANCIJIKEGAISHANNAOSHENJINGDIANSHENGLIHUODONG,CUJINNAOSUNSHANGSHUHOUHUANZHESUXING。


ZHONGXINGLUNAOSUNSHANGHOUHUANZHENAOZUZHIQUEXUEQUEYANG、CHIXUGAOLUYAJIJIFAXINGNAOGANSUNHAI,BINGCHUXIANHUNMI。WOMENDUINAOSUNSHANGHUNMIHUANZHECAIQUJIJIUYUHOUXUCUSUXINGYITIDEZHILIAOTIXI。


BINGQINGJIBENWENDINGHOUJIXINGYOUZHENGZHONGSHENJINGDIANCIJIZHILIAO,BINGJILULEYOUZHENGZHONGSHENJINGDIANCIJIZHILIAOZHONGXINGLUNAOSUNSHANGSHUHOUHUNMIHUANZHEDEYISHIPINGFENJINAODIANTU、NAOGANTINGJUEYOUFADIANWEIBIANHUATEZHENG,YITANTAOYOUZHENGZHONGSHENJINGDIANCIJIDUINAOSUNSHANGSHUHOUHUNMIHUANZHEDELINCHUANGLIAOXIAO。


1 CAILIAOYUFANGFA


1.1 YIBANZILIAO XUANQUBENYUAN 2011 NIAN2 YUEZHI2014 NIAN11 YUEQIJIANSHOUZHIDEZHONGXINGLUNAOSUNSHANGHUANZHE52 LI,QIZHONGNAN34 LI,NV 18 LI。 NARUBIAOZHUN:LUNAOSUNSHANGJIZHENSHUHOU 7 d,HUXIJIXUNHUANXITONGJIBENWENDING;GELASIGEHUNMIPINGFEN(GCS)≤8 FEN; LUNEIHUODONGXINGCHUXUETINGZHI; HUANZHEJIASHUZIYUANZHIQING,BINGQIANSHUZHIQINGTONGYISHU。


PAICHUBIAOZHUN:DUOQIGUANGONGNENGZHANGAI;YANZHONGBINGFAZHENG;JINQIDIANXIANFAZUO;NIANLINGZAI 10 SUIYIXIAHUOZHE 60SUIYISHANGZHE;YUNFU;WEIMANLIAOCHENG、ZHONGTUSIWANGHUOZIDONGCHUYUANZHE。


JIANGHUANZHESUIJIFENWEIDUIZHAOZUHEZHILIAOZU,MEIZU 26 LI,LIANGZUXINGBIE、NIANLING、LUNAOSUNSHANGLEIXING、SHUQIAN GCS PINGFEN、SHOUSHUFANGSHIDENGCHAYIJUNWUTONGJIXUEYIYI(P>0.05)。


1.2 ZHILIAOFANGFA


1.2.1 DUIZHAOZU JIYUCHANGGUIZHILIAOCUOSHI,BAOKUOKONGZHILUNEIYA、SHENJINGCUXINGYAOWUYINGYONG、GAOYAYANGZHILIAO、YUNDONGXUNLIANJIYUFANGBINGFAZHENGDENG。


1.2.2 ZHILIAOZU ZAICHANGGUIZHILIAOJICHUSHANGJIAXINGYOUZHENGZHONGSHENJINGDIANCIJI,ZHENGZHONGSHENJINGDIANCIJIYICAIYONGDIPINDIANCIJIZHILIAO,JIANGDIANJIZHIYUYOUCEWANGUANJIEZHANGMIANWANHENGWENSHANG 2 cm ZHENGZHONGSHENJINGDIAN,SHIJIAZHILIUDIANCIJI,CAIYONGBUDUICHENGFANGBO, BOKUAN 300 ms, CIJIQIANGDU 10~20 mA, PINLV 40 Hz, MEIFENZHONGGONGZUO 20 s, JINGXI 40 s, MEIRIXINGDIANCIJIZHILIAO 8 h,MEIZHOU 6 CI,2 ZHOUWEI 1 GELIAOCHENG,ZHILIAO 4 GELIAOCHENGHOUJINXINGPINGGU。


1.3 LINCHUANGGUANCHAXIANGMU


BINGRENRUXUANHOUJIGENJUFENZUJINXINGXIANGYINGZHILIAO,JILUZHILIAOQIANJIZHILIAO2 GEYUEHOUGCS PINGFEN、CRS-R PINGFEN[1]、NAODIANTU(EEG)、NAOGANTINGJUEYOUFADIANWEI CHULI,JILIANGZILIAOYI(x±s)BIAOSHI,CAIYONG t JIANYAN,JISHUZILIAOCAIYONG χ2 JIANYAN,P<0.05 WEICHAYIJUYOUTONGJIXUEYIYI。


2 JIE GUO


2.1 LIANGZUHUANZHEZHILIAOQIANHOU GCS PINGFENBIJIAO ZHILIAOHOULIANGZUHUANZHE GCS PINGFENJIAOZHILIAOQIANJUNYOUGAISHAN,QIEZHILIAOZUPINGFENJIAODUIZHAOZUMINGXIANSHENGGAO,CHAYIYOUTONGJIXUEYIYI(P<0.05,BIAO 1)。


2.2 LIANGZUHUANZHE CRS-R PINGFENBIJIAO ZHILIAOHOULIANGZUHUANZHECRS-R PINGFENJUNYOUGAISHAN, QIEZHILIAOZUPINGFENJIAODUIZHAOZUMINGXIANSHENGGAO,CHAYIYOUTONGJIXUEYIYI(P<0.05,BIAO 2)。


2.3 LIANGZUHUANZHEZHILIAOQIANHOU EEG BIJIAO ZHILIAOZUZHILIAOQIANHOU EEG BIJIAO,CHAYIYOUTONGJIXUEYIYI(P<0.05)。 ZHILIAOHOUZHILIAOZUYUDUIZHAOZUBIJIAO,CHAYIYIYOUTONGJIXUEYIYI(P < 0.05)。


EEG DEGAIBIANZHUYAOBIAOXIANWEIMANBO(θ、δ BO) JIANSHAO,α JIELVZENGDUO,HUOZHE α BOBOFUZENGGAO。


ZHI LIAO QIAN ZHI LIAO HOU


ZUBIE


ⅠJI


ⅡJI


ⅢJI


ⅣJI


ⅤJI



Ⅰ级


ⅡJI


ⅢJI


ⅣJI


ⅤJI



治疗组


2


3


11


8


2



11


9


3


3


0



对照组


1


3


10


9


3



5


7


10


3


1



2.4 两组患者治疗前后 BAEP 比较 治疗组治疗前后 BAEP 比较,差异有统计学意义(P<0.05)。 治疗后治疗组与对照组比较, 差异亦有统计学意义(P<0.05)。


3 TAO LUN


HUNMISHINAOSUNSHANGHOUWUGANZHIZHUANGTAI,HUANZHEBIAOXIANWEIDUIZISHENJIWAIJIERENZHIGONGNENGSANGSHI。ZHONGXINGLUNAOSUNSHANGKEZHIDANAOBANQIUGUANGFANSHENJINGYUANSUNSHANG、NAOGANWANGZHUANGJIHUOXITONGGONGNENGBEIZUDUAN,SHICHANGJIANDEZHIHUNMIYUANYIN,HUNMICUIXINGSHISHENJINGWAIKEYISHENGBUDUANTANSUODEKETI。


SHENJINGDIANCIJIZUOWEICUIXINGCUOSHIBEISHOUGUANZHU,DIANCIJIFENWEINAOSHENBUDIANCIJI、JISUIDIANCIJIHEJINGPIDIANCIJI,NAOSHENBUDIANCIJIHEJISUIDIANCIJIXUSHOUSHUZHIRUDIANJI,YOUYUQIBINGFAZHENGDUOYINERLINCHUANGYINGYONGBUGUANGFAN。


ZHENGZHONGSHENJINGDIANCIJISHUJINGPIDIANCIJI,ZI1996 NIANYokoyama SHOUCIBAODAOZHENGZHONGSHENJINGDIANCIJIZHILIAOHUNMIHUANZHEYILAI,ZUOWEIYIXIANGWUCHUANG、YICAOZUO、FEIYONGDI、BINGFAZHENGSHAODEZHILIAOJISHU,ZHENGZHONGSHENJINGDIANCIJICUSUXINGBINGLIBAODAOZHUJIANZENGDUO。


SHANGHAIRENJIYIYUANYINGYONGYOUZHENGZHONGSHENJINGDIANCIJIDUINAOSUNSHANGHUNMIHUANZHECUIXINGZHILIAOJIAOZAO、BAODAOBINGLISHUJIAODUO(465 LI)[4-5],XINGYOUZHENGZHONGSHENJINGDIANCIJIZHILIAOHOU,SPECT-CT XIANXIANGGUANCHASHUANGCEGANJUEYUNDONGQU、QIUNAO、ZHENYEPIZHI、DINGSHANGXIAOYEXUELIUGUANZHUZENGJIA,NAOGANYOUFADIANWEIPINGGUGAISHANJIAOWEIMINGXIAN。


BENYANJIUJIEGUOXIANSHI,YOUZHENGZHONGSHENJINGDIANCIJIDUILUNAOSUNSHANGSHUHOUHUNMIHUANZHEJUYOULIANGHAODELINCHUANGCUXINGLIAOXIAO,YOULIYUSHENJINGGONGNENGDEKANGFU,GAISHANLINCHUANGYUHOU,ZHIDELINCHUANGGEJIYIYUANTUIGUANGYINGYONG。


CANKAOWENXIAN


LEIJIN,GAOGUOYI,SONGSHAOLI,DENG. ZHENGZHONGSHENJINGDIANCIJIDUILUNAOCHUANGSHANGHUNMIHUANZHENAOXUELIUGUANZHUDEYINGXIANG:SPECT-CT XIANXIANGGUANCHA[J]. ZHONGHUASHENJINGWAIKEZAZHI,2012,28(2):112-115.


GAOGUOYI,BAOYINGHUI,LIANGYUMIN,DENG. YOUZHENGZHONGSHENJINGDIANCIJIZAOQIGANYUDUILUNAOSUNSHANGHUNMIHUANZHEDELINCHUANGLIAOXIAOGUANCHA[J]. ZHONGHUACHUANGSHANGZAZHI,2012,2


LUNAOSUNSHANGHOUHUNMIBINGRENSHENJINGDIZHIDEBIANHUA[J]. QIQIHAERYIXUEYUANXUEBAO,2006,27 (13):1548-1549.


LICHUNYU,HAOYAZHOU,ZHANGZHIQIANG,DENG. GAOYAYANGJIYOUZHENGZHONGSHENJINGDIANCIJIDUIZHONGXINGLUNAOWAISHANGHUANZHEDESHUHOUCUIXINGTANSUO[J]. XIANDAIZHONGXIYIJIEHEZAZHI,2014,23


右正中神经电刺激对脑损伤术后昏迷患者催醒的临床研究 2019-11-18 本文被阅读 326 次
 
 
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